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The evidence map

431 supplements, graded by the evidence

A licensed doctor read the human research on 431 supplements, herbs and substances and graded each one — so you can see at a glance what's proven, what's debunked, and what's banned. Free, no ads, nothing for sale.

Tap any substance for its full evidence, dosing & safety. How grading works · Who made this · Educational reference, not medical advice.

Strong 36

solid proof it works

artichokeBeta-AlanineBeta-Glucan (Oat / Barley)CaffeineCopperCreatine MonohydrateDe Simone Formulation (VSL#3 / Visbiome)E. coli Nissle 1917edamameFolate / Folic AcidGlucomannan (Konjac)green-peasIodineIronLactobacillus rhamnosus GGLactuloseLavender (Silexan)MelatoninMulti-strain Probiotics (general)Omega-3 (EPA/DHA)PhosphorusPlant Sterols (Phytosterols)potatoPsyllium (Fiber)Saccharomyces boulardiispinachsweet-potatoVitamin A (Retinol / Beta-Carotene)Vitamin B1 (Thiamine)Vitamin B12Vitamin B3 (Niacin)Vitamin B6 (Pyridoxine)Vitamin D3Vitamin K1 (Phylloquinone)Wheat Bran (Insoluble Fiber)zucchini

Moderate 180

likely helps, modestly

Acacia Fiber (Gum Arabic)Acesulfame Potassium (Ace-K)Acetyl-L-Carnitine (ALCAR)Algal Oil (Vegan Omega-3)AlluloseAlmondAmla (Indian Gooseberry)AndrographisAppleArabinoxylanarugulaAshwagandhaasparagusAvocadoBacillus coagulansBacopa MonnieriBananaBee PropolisBeetroot / Dietary Nitratebell-pepperBerberineBetaine (TMG)Bifidobacterium infantis 35624Bifidobacterium lactis BB-12Bifidobacterium lactis DN-173 010Bifidobacterium longum BB536Black Seed OilBlackberryBlackcurrantBlueberrybok-choyBoswelliaBovine ColostrumbroccoliBromelainbrussels-sproutsButterburbutternut-squashcabbageCalciumCantaloupe MelonCaramel Color (4-MEI)CarnosinecarrotCashewcauliflowerceleryCelery Seed ExtractChamomileChasteberry (Vitex)ChlorellaCholineCitrus BergamotCod Liver OilCoenzyme Q10Collagen Peptidescollard-greensCranberryCurcumin (Turmeric)DGL (Deglycyrrhizinated Licorice)Digestive EnzymeseggplantfennelFenugreekFlaxseed (ALA)Fructooligosaccharides (FOS)Galactooligosaccharides (GOS)GarlicGingerGlycerolGrape Seed ExtractGrapefruitgreen-beansGuar GumGuavaGymnema SylvestreHawthornHazelnutHigh-Fructose Corn SyrupHoly Basil (Tulsi)Horse ChestnutHuman Milk Oligosaccharides (2'-FL)Inositol (Myo-Inositol)Inulin (Chicory Root Fiber)kaleKavaKiwifruitKrill OilL-ArginineL-CarnitineL-CitrullineL-TheanineL-TryptophanLactobacillus casei ShirotaLactobacillus paracaseiLactobacillus plantarum 299vLactobacillus reuteri DSM 17938Larch ArabinogalactanleekLemonLemon BalmLicorice RootLutein & ZeaxanthinMagnesiumMaltitolMandarin OrangeMethylcellulose (Citrucel)MolybdenumMonk Fruit (Luo Han Guo)Montmorency Cherry ExtractMSG (Monosodium Glutamate)Mucuna PruriensMulberryN-Acetylcysteine (NAC)Niacinamide (Nicotinamide)okraOlive Leaf ExtractOlivesonionOrangePantethinePapayaPartially Hydrolyzed Guar Gum (PHGG)PassionflowerPeanutPearPecanPectinPeppermint OilPhosphatidylserinePhosphoric AcidPistachioPlantainPlumPolydextrosePolypodium leucotomosPomegranatePotassiumPotassium SorbatePrune (Dried Plum)pumpkinQuercetinradishRed GrapeRed Yeast RiceResistant Maltodextrin (Soluble Corn Fiber)Resistant Starchromaine-lettuceSaccharinSaffronSodium BenzoateSodium BicarbonateSorbitolSt. John's WortStevia (Steviol Glycosides)Stinging NettleStrawberryStrontiumSucraloseSulfitesSweet Cherrysweet-cornswiss-chardTart CherrytomatoturnipUC-II (Undenatured Collagen)Vitamin B2 (Riboflavin)Vitamin B5 (Pantothenic Acid)Vitamin CWalnutwatercressWatermelonWheat Dextrin (Benefiber)White Willow Barkwhite-mushroomXanthan GumXylooligosaccharides (XOS)ZincZinc Carnosine

Preliminary 115

early signs, not proven

5-HTPAcai BerryAgaricus blazeiAgmatine SulfateAkkermansia muciniphilaAlpha-GPCAmbarellaAniracetamApigeninApricotAstaxanthinAstragalusBacillus subtilisBee PollenBetaine HClBilimbiBoronBrazil NutBreadfruitCalamansiCalcium D-GlucarateCat's ClawCBG (Cannabigerol)CempedakChagaChanca PiedraCherimoyaChestnutcucumberDatesDeer Antler VelvetDragon Fruit (Pitaya)DurianEcdysteroneEdible Bird's NestEjiao (Donkey-hide Gelatin)Elderberry (Sambucus)Emulsifiers (Polysorbate-80 & CMC)FigFisetinGandariaGlutathione (Skin Whitening)GlycineGoji BerryGooseberryGotu KolaHe Shou Wu (Fo-Ti)Honeydew MelonHorny Goat WeedIndian Jujube (Ber)Isomaltooligosaccharides (IMO)JackfruitJambolan (Jamun / Java Plum)JiaogulanL-TyrosineLangsat / DukuLimeLion's ManeLithium OrotateLonganLycheeLycopene & CarotenoidsMacaMacadamiaMagnolia BarkMaitakeManganeseMangoMangosteenMethylene BlueNectarineNicotinamide Riboside (NR)NMN (Nicotinamide Mononucleotide)NoopeptOregano OilPanax GinsengPassion FruitPersimmonPhenylpiracetamPhytoceramidesPine NutPineapplePomeloPQQPterostilbenePulasanPycnogenol (Pine Bark)RambutanRaspberryReishiRhodiola RoseaRoyal JellySalak (Snake Fruit)SantolSapodilla (Ciku)SchisandraSea Buckthorn OilShiitakeShilajitSilica (Horsetail / ch-OSA)Slippery ElmSoursop (Graviola)SpermidineSpirulinaStarfruit (Carambola)Sugar Apple (Custard Apple)TamarindTaurineTongkat AliTremella (Snow Fungus)TriphalaTurkey Tail (PSK/PSP)Urolithin AVitamin K2Wax Apple

Mixed 69

studies disagree

Agave NectarAlpha-Lipoic AcidApple Cider VinegarArtificial Food DyesAspartameBCAAsBHA & BHTBilberryBitter MelonBlack CohoshButyrate (Tributyrin)CarrageenanCBD (Cannabidiol)CBN (Cannabinol)ChromiumCinnamonCiticoline (CDP-Choline)CLACoconutCordycepsD-Aspartic AcidDHEADIM (Diindolylmethane)Dong QuaiEchinaceaEleuthero (Siberian Ginseng)ErythritolEvening Primrose Oil (GLA)FeverfewGABA (supplement)Ginkgo BilobaGlucosamine & ChondroitinGlutamineGreen Tea Extract (EGCG)GuggulHMBHuperzine AHyaluronic Acid (Oral)KratomL-LysineL. helveticus R0052 + B. longum R0175Lactobacillus acidophilus NCFMLeucineMaltodextrinMCT OilMilk Thistle (Silymarin)MoringaMSM (Methylsulfonylmethane)NattokinasePeachPiracetamPolicosanolProbioticsRed CloverResveratrolSaw PalmettoSea Buckthorn BerrySeleniumSerrapeptaseSodium Nitrite & NitrateSulbutiamineSulforaphaneTribulus TerrestrisValerian RootVanadiumVinpocetineVitamin E (Tocopherol)XylitolYohimbe / Yohimbine

No Evidence 18

no good proof it works

Activated CharcoalAlkaline Water / DietBiotin (Vitamin B7)Colloidal SilverDetox / 'Teatox' CleansesGarcinia Cambogia (HCA)HomeopathyLaetrile / 'Vitamin B17'Liquid ChlorophyllNitrous Oxide (Recreational)Pangolin ScalesPhenibutRaspberry KetonesRhino HornSea Moss (Irish Moss)SeahorseShark CartilageTiger Bone

Banned / Harmful 13

unsafe / banned

Anabolic Steroids (AAS)Bear BileClenbuterolCocaineDNP (2,4-Dinitrophenol)Ephedra / EphedrineHeroin & Illicit FentanylHuman Growth Hormone (HGH)MDMA (Ecstasy / Molly)MethamphetamineSARMsTianeptineTitanium Dioxide

NutriDex — free, non-profit, clinician-curated. nutridex.info · Evidence tiers reflect the weight of published human research, not a recommendation. Talk to your doctor or pharmacist.