NutriDex

The Supplement Research Compendium

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asparagus

Folate- and vitamin-K-dense spring spear with prebiotic fructans and emerging cardiometabolic signals.

Moderate evidence 🥦Vegetables
Evidence tier
Moderate
Research weight
Citations
11 verified / 11
Classification
Vegetables
What the evidence says. Several controlled trials; effects real but modest or context-dependent.

Nutrition per serving 1 cup, cooked (boiled, drained) (180 g)

180gSERVING
  • Sugars 2.3 g1%
  • Fibre 3.6 g2%
  • Other carbs 1.5 g1%
  • Protein 4.3 g2%
  • Other 168.3 g94%
What's in one serving, by weight — average composition (USDA).
Vitamin C15%Fiber13%Potassium9%Folate67%Vitamin A10%Vitamin K76%Vitamin B68%Manganese12%
One serving as % of the adult daily requirement (FDA Daily Values). The bold outer ring = 100% of a day's needs.
40 kcal4.3 g protein3.6 g fiber2.3 g sugar
NutrientPer serving% daily value
Vitamin C14 mg15%
Fiber3.6 g13%
Potassium403 mg9%
Folate268 µg67%
Vitamin A90 µg10%
Vitamin K91 µg76%
Vitamin B60.14 mg8%
Manganese0.28 mg12%
Copper0.3 mg33%
Vitamin E2.7 mg18%
Magnesium25 mg6%
Calcium41 mg3%

Composition data: USDA FoodData Central ↗

What is asparagus?

asparagus is a vegetable used for asparagus-powder rct lowered fasting and post-load glucose, triglycerides and oxidative stress over 12 weeks. NutriDex grades the human evidence as Moderate. Asparagus is exceptionally nutrient-dense for its low calorie load, delivering large fractions of daily folate and vitamin K plus prebiotic inulin-type fructans, the flavonol quercetin/rutin, and saponins. Direct human trials of whole asparagus are scarce: the strongest is a 2025 double-blind RCT (n=44) in which 12 weeks of asparagus powder lowered fasting glucose, post-load glucose AUC, triglycerides and oxidative stress versus placebo, though it was small and exploratory. Most of the supporting evidence is indirect, drawn from meta-analyses of asparagus's signature constituents—prebiotic inulin-type fructans improving glycemic markers, quercetin modestly lowering blood pressure, and high dietary-fibre/folate intakes linked to lower cardiovascular and stroke risk in pooled cohorts and trials. Overall the human evidence is moderate and largely surrogate-endpoint or constituent-based rather than proof that asparagus itself changes hard outcomes.

Purported Benefits

Asparagus-powder RCT lowered fasting and post-load glucose, triglycerides and oxidative stress over 12 weeks
Outstanding source of folate (~67% DV/cup) supporting homocysteine metabolism
Very high in vitamin K (~76% DV/cup) for coagulation and bone
Prebiotic inulin-type fructans nourish gut microbiota and aid glycemic control (constituent meta-analyses)
Quercetin/rutin flavonols associated with modest blood-pressure lowering

Dosing & Compounds

Typical Dose
Standard serving: 1 cup, cooked (boiled, drained) (180 g). Eat whole (with skin where edible); favour whole fruit over juice.
Active Compounds
Inulin-type fructans (prebiotic fibre)Quercetin and rutin (flavonols)Steroidal saponins (protodioscin)Folate (vitamin B9)Vitamin K1 (phylloquinone)GlutathioneAsparagusic acidVitamin C and vitamin E (alpha-tocopherol)

Safety & Cautions

Generally very safe as food. High vitamin K1 content can interfere with warfarin/vitamin-K-antagonist dosing—keep intake consistent. The fructan (FODMAP) content can trigger bloating, gas and diarrhoea in IBS-sensitive people. Asparagusic acid produces a harmless sulphurous urine odour in many people. Purines are moderate and large amounts may modestly raise uric acid in gout-prone individuals. Rare contact or IgE allergy to asparagus has been reported. Educational only — always check with your doctor or pharmacist before combining asparagus with any medicine.

Key Studies ★ 11 studies

Meta-analysis Zhao 2024 ✓ PubMed
Systematic review and meta-analysis of 21 RCTs worldwide found folic acid supplementation significantly reduced stroke risk, with the effect most evident in regions without mandatory folate fortification.
Meta-analysis Huang 2023 ✓ PubMed
Updated systematic review and meta-analysis of prospective cohorts found higher dietary fibre intake was associated with lower all-cause (RR 0.90), cardiovascular (RR 0.87) and cancer (RR 0.91) mortality.
Meta-analysis Wang 2019 ✓ Full text
GRADE-assessed systematic review and dose-response meta-analysis of 33 RCTs found inulin-type fructans (asparagus's main fibre) significantly reduced fasting glucose, HbA1c, fasting insulin and HOMA-IR in prediabetes/type 2 diabetes.
Meta-analysis Serban 2016 ✓ PubMed
Meta-analysis of 7 RCTs (9 arms, 587 patients) found quercetin supplementation lowered systolic BP by 3.04 mmHg (95% CI -5.75 to -0.33) and diastolic BP by 2.63 mmHg (95% CI -3.26 to -2.01).
Meta-analysis Reynolds 2019 ✓ Source
Lancet series of systematic reviews/meta-analyses (~135 million person-years) found highest vs lowest dietary fibre intake was associated with a 15-30% reduction in all-cause and cardiovascular mortality, with greatest benefit at 25-29 g/day.
RCT Mongraykang 2025 ✓ Full text
Double-blind RCT (n=44) of 40 mg/kg/day asparagus powder for 12 weeks significantly lowered fasting glucose (p=0.045), post-load glucose AUC (p<0.05), triglycerides (p=0.043) and malondialdehyde (p=0.009) versus placebo.
RCT Int J Mol Sci 2025 ✓ Full text
RCT in 72 overweight/obese adults (4 arms): Asparagus officinalis root extract significantly lowered blood glucose and lipids only when combined with HIIT, whereas extract alone did not improve (and tended to raise) lipid levels.
RCT J Nutr Sci Vitaminol 2025 ✓ PubMed
12-week double-blind RCT in 20 resistance-trained males: asparagus-derived 20-hydroxyecdysone 30 mg/day increased fat oxidation at rest and during exercise and reduced arm/leg/abdominal fat vs placebo.
RCT Sports (Basel) 2025 ✓ Full text
RCT in 72 obese/overweight individuals: HIIT combined with Asparagus officinalis extract improved cardiovascular and pulmonary function parameters vs control arms.
RCT Sasazuki/J Nutr Sci Vitaminol 2023 ✓ Full text
RCT in healthy males: Asparagus officinalis extract supplementation improved muscle mass and strength retention following resistance training and detraining vs control.
Prospective cohort Bazzano 2002 ✓ PubMed
NHANES I Epidemiologic Follow-up cohort (n=9,764) found participants in the highest quartile of dietary folate intake had a 20% lower stroke incidence and significantly lower cardiovascular disease risk than the lowest quartile.

Common questions about asparagus

What is asparagus used for?

asparagus is most often taken for Asparagus-powder RCT lowered fasting and post-load glucose, triglycerides and oxidative stress over 12 weeks, Outstanding source of folate (~67% DV/cup) supporting homocysteine metabolism, Very high in vitamin K (~76% DV/cup) for coagulation and bone, Prebiotic inulin-type fructans nourish gut microbiota and aid glycemic control (constituent meta-analyses). Folate- and vitamin-K-dense spring spear with prebiotic fructans and emerging cardiometabolic signals.

Does asparagus work — what does the evidence say?

Moderate evidence. Several controlled trials; effects real but modest or context-dependent. Asparagus is exceptionally nutrient-dense for its low calorie load, delivering large fractions of daily folate and vitamin K plus prebiotic inulin-type fructans, the flavonol quercetin/rutin, and saponins. Direct human trials of whole asparagus are scarce: the strongest is a 2025 double-blind RCT (n=44) in which 12 weeks of asparagus powder lowered fasting glucose, post-load glucose AUC, triglycerides and oxidative stress versus placebo, though it was small and exploratory. Most of the supporting evidence is indirect, drawn from meta-analyses of asparagus's signature constituents—prebiotic inulin-type fructans improving glycemic markers, quercetin modestly lowering blood pressure, and high dietary-fibre/folate intakes linked to lower cardiovascular and stroke risk in pooled cohorts and trials. Overall the human evidence is moderate and largely surrogate-endpoint or constituent-based rather than proof that asparagus itself changes hard outcomes.

What is the typical dose of asparagus?

Standard serving: 1 cup, cooked (boiled, drained) (180 g). Eat whole (with skin where edible); favour whole fruit over juice.

Is asparagus safe? Any cautions or side effects?

Generally very safe as food. High vitamin K1 content can interfere with warfarin/vitamin-K-antagonist dosing—keep intake consistent. The fructan (FODMAP) content can trigger bloating, gas and diarrhoea in IBS-sensitive people. Asparagusic acid produces a harmless sulphurous urine odour in many people. Purines are moderate and large amounts may modestly raise uric acid in gout-prone individuals. Rare contact or IgE allergy to asparagus has been reported.

How many studies support asparagus?

NutriDex cites 11 sources for asparagus, graded "Moderate".

Cite this page
APA

Peh, D. (2026). asparagus: Benefits, Dosage, Side Effects & Evidence. NutriDex — The Supplement Research Compendium. Retrieved 26 Jun 2026, from https://nutridex.info/s/asparagus

BibTeX
@misc{nutridex_asparagus,
  author       = {Peh, Daryl},
  title        = {asparagus: Benefits, Dosage, Side Effects \& Evidence},
  year         = {2026},
  howpublished = {NutriDex --- The Supplement Research Compendium},
  url          = {https://nutridex.info/s/asparagus},
  note         = {Reviewed by Dr Daryl Peh, MBBS Singapore, MMed FM. Accessed 2026-06-26}
}

For medical claims, citing the underlying primary studies linked above is preferred. NutriDex is an educational reference, not medical advice.

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