NutriDex

The Supplement Research Compendium

🧅

leek

Mild allium with vitamin K and folate, riding the broader garlic/onion evidence base.

Moderate evidence 🥦Vegetables
Evidence tier
Moderate
Research weight
Citations
11 verified / 11
Classification
Vegetables
What the evidence says. Several controlled trials; effects real but modest or context-dependent.

Nutrition per serving 1 cup chopped, raw (89 g)

89gSERVING
  • Sugars 3.5 g4%
  • Fibre 1.6 g2%
  • Other carbs 7.5 g8%
  • Protein 1.3 g1%
  • Other 75.1 g84%
What's in one serving, by weight — average composition (USDA).
Vitamin C12%Fiber6%Potassium3%Folate14%Vitamin A8%Vitamin K35%Vitamin B612%Manganese19%
One serving as % of the adult daily requirement (FDA Daily Values). The bold outer ring = 100% of a day's needs.
54 kcal1.3 g protein1.6 g fiber3.5 g sugar
NutrientPer serving% daily value
Vitamin C11 mg12%
Fiber1.6 g6%
Potassium160 mg3%
Folate57 µg14%
Vitamin A74 µg8%
Vitamin K42 µg35%
Vitamin B60.2 mg12%
Manganese0.43 mg19%
Copper0.11 mg12%
Vitamin E0.82 mg5%
Magnesium25 mg6%
Calcium53 mg4%

Composition data: USDA FoodData Central ↗

What is leek?

leek is a vegetable used for allium-rich diets linked to markedly lower gastric cancer risk in pooled analyses. NutriDex grades the human evidence as Moderate. Leeks are a member of the Allium genus alongside garlic and onion, and most human evidence is generated by those better-studied relatives rather than by leeks directly. Pooled data show allium-rich diets are associated with substantially lower gastric cancer risk (umbrella review RR 0.78, 95% CI 0.67-0.91), and randomized trials of concentrated garlic preparations lower systolic blood pressure by roughly 3.8-8.4 mmHg and LDL/total cholesterol modestly, with the largest effects in hypertensive or dyslipidemic patients. Evidence specific to leek-level dietary intake is largely observational and confounded; the cardiometabolic signals come from supplement-dose garlic, so culinary leek portions should be viewed as part of a healthy vegetable-rich pattern rather than a proven therapeutic.

Purported Benefits

Allium-rich diets linked to markedly lower gastric cancer risk in pooled analyses
Concentrated allium (garlic) lowers blood pressure in hypertensive adults in RCTs
Garlic-class allium modestly reduces total and LDL cholesterol
Good source of vitamin K and folate for a low-calorie vegetable
Contributes prebiotic inulin-type fibre and flavonols to a vegetable-rich diet

Dosing & Compounds

Typical Dose
Standard serving: 1 cup chopped, raw (89 g). Eat whole (with skin where edible); favour whole fruit over juice.
Active Compounds
Organosulfur compounds (alliin / allicin, diallyl disulfide)Kaempferol and quercetin (flavonols)Inulin-type fructans (prebiotic fibre)Vitamin K1 (phylloquinone)FolateSaponins

Safety & Cautions

Generally very safe as food. The inulin-type fructans make leeks high-FODMAP, so they can trigger bloating, gas, or diarrhea in people with IBS. The vitamin K content (about 42 ug per cup) can interfere with warfarin dosing, so intake should be kept consistent. Concentrated garlic/allium supplements (not culinary leeks) can increase bleeding risk and should be paused before surgery. Rare allium contact or IgE allergy occurs. Educational only — always check with your doctor or pharmacist before combining leek with any medicine.

Key Studies ★ 11 studies

updated meta-analysis and review Halsted CH 2023 ✓ Source
Updated pooled analysis confirmed garlic lowers blood pressure in hypertensive individuals and modestly improves serum cholesterol, supporting an adjunct cardioprotective role for allium.
Meta-analysis Wan 2022 (Front Nutr) ✓ PubMed
Systematic review and meta-analysis of 22 studies found no significant association between high allium vegetable intake and overall cancer risk (RR 0.97; 95% CI 0.92-1.03), with no linear or nonlinear dose-response relationship.
umbrella review of meta-analyses Wan Q 2019 ✓ Full text
Across 16 meta-analyses (50 outcomes), high allium vegetable intake was associated with lower gastric cancer risk (RR 0.78, 95% CI 0.67-0.91) and garlic lowered total cholesterol by 17.2 mg/dL after >8 weeks.
meta-analysis of RCTs Wang J 2015 ✓ Full text
In 17 randomized trials, garlic supplementation reduced systolic BP by 3.75 mmHg (95% CI -5.04 to -2.45) and diastolic BP by 3.39 mmHg (95% CI -4.14 to -2.65) versus control, with larger effects in hypertensive patients.
meta-analysis of RCTs Sun YE 2018 ✓ PubMed
Pooled analysis of 39 trials found garlic reduced total cholesterol by about 17 mg/dL and LDL-C by about 9 mg/dL in adults with elevated baseline cholesterol over at least 2 months.
systematic review and meta-analysis Turati F 2015 ✓ Source
Higher allium vegetable consumption was inversely associated with gastric cancer risk, with a pooled case-control odds ratio of 0.54 (95% CI 0.43-0.65) comparing highest versus lowest intake.
meta-analysis of prospective studies Wu X 2015 ✓ PubMed
Pooled prospective-cohort data found no significant association between allium vegetable intake and colorectal cancer risk, tempering claims from case-control data.
meta-analysis of prospective cohorts Wang PY 2016 ✓ Source
Each additional serving per day of vegetables was associated with a ~10% lower type 2 diabetes risk (RR 0.90, 95% CI 0.80-1.01), with green/leafy and allium-type vegetables contributing to the protective pattern.
RCT Bordbar 2023 ✓ Full text
In a double-blind RCT of 97 children with chemotherapy-induced febrile neutropenia, Allium ampeloprasum (leek) capsules (500 mg twice daily) achieved neutrophil recovery within 7 days in 83.6% vs 54.2% of placebo controls (P<0.001) and earlier discharge (67.3% vs 48%, P=0.028).
RCT Li 2023 (AJCN) ✓ PubMed
In a 22.3-year continuous follow-up of the randomized Shandong Intervention Trial (3229 subjects, 144 incident gastric cancers), garlic-allium vegetable intake was associated with lower gastric cancer risk (OR 0.83; 95% CI 0.70-0.98 per 1 kg/y increment; P-trend=0.02), while scallion intake showed no association.
Observational Ferro 2022 (StoP Project) ✓ Full text
Pooled analysis of the Stomach cancer Pooling (StoP) Project found non-significant inverse associations for any vs no consumption of allium vegetables (OR 0.84; 95% CI 0.66-1.08), onions (OR 0.88; 95% CI 0.77-1.01), and garlic (OR 0.92; 95% CI 0.80-1.06).

Common questions about leek

What is leek used for?

leek is most often taken for Allium-rich diets linked to markedly lower gastric cancer risk in pooled analyses, Concentrated allium (garlic) lowers blood pressure in hypertensive adults in RCTs, Garlic-class allium modestly reduces total and LDL cholesterol, Good source of vitamin K and folate for a low-calorie vegetable. Mild allium with vitamin K and folate, riding the broader garlic/onion evidence base.

Does leek work — what does the evidence say?

Moderate evidence. Several controlled trials; effects real but modest or context-dependent. Leeks are a member of the Allium genus alongside garlic and onion, and most human evidence is generated by those better-studied relatives rather than by leeks directly. Pooled data show allium-rich diets are associated with substantially lower gastric cancer risk (umbrella review RR 0.78, 95% CI 0.67-0.91), and randomized trials of concentrated garlic preparations lower systolic blood pressure by roughly 3.8-8.4 mmHg and LDL/total cholesterol modestly, with the largest effects in hypertensive or dyslipidemic patients. Evidence specific to leek-level dietary intake is largely observational and confounded; the cardiometabolic signals come from supplement-dose garlic, so culinary leek portions should be viewed as part of a healthy vegetable-rich pattern rather than a proven therapeutic.

What is the typical dose of leek?

Standard serving: 1 cup chopped, raw (89 g). Eat whole (with skin where edible); favour whole fruit over juice.

Is leek safe? Any cautions or side effects?

Generally very safe as food. The inulin-type fructans make leeks high-FODMAP, so they can trigger bloating, gas, or diarrhea in people with IBS. The vitamin K content (about 42 ug per cup) can interfere with warfarin dosing, so intake should be kept consistent. Concentrated garlic/allium supplements (not culinary leeks) can increase bleeding risk and should be paused before surgery. Rare allium contact or IgE allergy occurs.

How many studies support leek?

NutriDex cites 11 sources for leek, graded "Moderate".

Cite this page
APA

Peh, D. (2026). leek: Benefits, Dosage, Side Effects & Evidence. NutriDex — The Supplement Research Compendium. Retrieved 26 Jun 2026, from https://nutridex.info/s/leek

BibTeX
@misc{nutridex_leek,
  author       = {Peh, Daryl},
  title        = {leek: Benefits, Dosage, Side Effects \& Evidence},
  year         = {2026},
  howpublished = {NutriDex --- The Supplement Research Compendium},
  url          = {https://nutridex.info/s/leek},
  note         = {Reviewed by Dr Daryl Peh, MBBS Singapore, MMed FM. Accessed 2026-06-26}
}

For medical claims, citing the underlying primary studies linked above is preferred. NutriDex is an educational reference, not medical advice.

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