NutriDex

The Supplement Research Compendium

Supplement–drug interactions

Supplements That Interact with Immunosuppressants (transplant / autoimmune)

5 supplements in NutriDex have a known or theoretical interaction with immunosuppressants (transplant / autoimmune), including 1 best avoided entirely. Grouped by severity below; each links to its full evidence, dosing & mechanism. This is educational and not exhaustive — always tell your doctor or pharmacist about every supplement you take before combining it with medication.

Avoid — do not combine 1

St. John's Wort

Drops drug levels below therapeutic range — documented transplant rejection.

Caution — use only with medical guidance 3

Astragalus

Immunostimulant activity may counteract immunosuppressant therapy in transplant/autoimmune patients.

Cat's Claw

May stimulate the immune system, potentially opposing immunosuppressant drugs and worsening autoimmune disease.

Echinacea

May stimulate immune activity and theoretically blunt immunosuppressant therapy (transplant/autoimmune).

Monitor — watch for effects 1

Spirulina

Immune-stimulating activity may theoretically oppose immunosuppressant therapy.

Each supplement links to its full evidence, dosing, mechanism & citations. See also all medication interaction guides →