Supplement–drug interactions
Supplements That Interact with Antiplatelet drugs (aspirin, clopidogrel)
17 supplements in NutriDex have a known or theoretical interaction with antiplatelet drugs (aspirin, clopidogrel), including 1 best avoided entirely. Grouped by severity below; each links to its full evidence, dosing & mechanism. This is educational and not exhaustive — always tell your doctor or pharmacist about every supplement you take before combining it with medication.
Avoid — do not combine 1
Avoid white willow if you are allergic to aspirin or NSAIDs; it can trigger the same reaction.
Caution — use only with medical guidance 10
Bromelain with aspirin or clopidogrel may add to bleeding tendency.
Chaga with aspirin or clopidogrel may increase bleeding tendency.
Feverfew with aspirin or clopidogrel may add to bleeding tendency.
Concentrated garlic supplements may increase bleeding risk with blood thinners.
Ginkgo may increase bleeding risk, with case reports of serious bleeding alongside blood thinners.
Horse chestnut with aspirin or clopidogrel may add to bleeding tendency.
Nattokinase plus aspirin or clopidogrel may significantly increase bleeding; a hemorrhage case is reported.
Policosanol inhibits platelet aggregation and may add to aspirin or clopidogrel, raising bleeding risk.
High-dose quercetin can inhibit platelets and enhance aspirin's antiplatelet effect, raising bleeding risk.
Serrapeptase with aspirin or clopidogrel may increase bleeding tendency.
Monitor — watch for effects 6
Algae oil with aspirin or clopidogrel may modestly increase bleeding tendency at high doses.
Cod liver oil with aspirin or clopidogrel may modestly increase bleeding tendency at high doses.
High-dose curcumin/turmeric may increase bleeding risk with blood thinners.
Flaxseed with aspirin or clopidogrel may modestly increase bleeding tendency at high doses.
High-dose ginger may modestly add to bleeding risk with anticoagulants or antiplatelets.
Krill oil with aspirin or clopidogrel may modestly increase bleeding tendency at high doses.
Each supplement links to its full evidence, dosing, mechanism & citations. See also all medication interaction guides →