NutriDex

The Supplement Research Compendium

Supplement–drug interactions

Supplements That Interact with Blood-pressure drugs

7 supplements in NutriDex have a known or theoretical interaction with blood-pressure drugs, including 2 best avoided entirely. Grouped by severity below; each links to its full evidence, dosing & mechanism. This is educational and not exhaustive — always tell your doctor or pharmacist about every supplement you take before combining it with medication.

Avoid — do not combine 2

Licorice Root

Glycyrrhizin raises blood pressure and opposes antihypertensive therapy.

Yohimbe / Yohimbine

Yohimbine raises blood pressure and heart rate, opposing antihypertensive therapy.

Caution — use only with medical guidance 3

Green Tea Extract (EGCG)

Green tea sharply reduces nadolol absorption (~85%), blunting its BP-lowering effect.

Hawthorn

May add to BP-lowering and vasodilator drugs, risking hypotension.

L-Arginine

L-arginine can lower blood pressure and may add to antihypertensive drugs, risking hypotension.

Monitor — watch for effects 2

Beetroot / Dietary Nitrate

Dietary nitrate may add to BP-lowering drugs, risking mild hypotension.

Garlic

Garlic may modestly lower blood pressure, adding to antihypertensive drugs.

Each supplement links to its full evidence, dosing, mechanism & citations. See also all medication interaction guides →